Description
Product details
GHK-Cu — Copper Tripeptide Complex
GHK-Cu (glycyl-L-histidyl-L-lysine : copper(II)) is a naturally occurring tripeptide first isolated from human plasma, where its concentration declines measurably with age. Across four decades of research literature, GHK-Cu has emerged as one of the most broadly studied regenerative peptides due to its gene-regulatory activity and its role as a high-affinity copper carrier to sites of tissue damage.
Mechanism of Action
GHK-Cu acts as a bioactive signaling molecule that modulates expression of an estimated 30% of the human genome under injury or stress conditions. Well-documented pathways include upregulation of collagen I/III and decorin, induction of metalloproteinases (MMP-2) and their tissue inhibitors (TIMPs) for organized matrix remodeling, and activation of lysyl oxidase for collagen crosslinking. The complexed copper ion serves as a cofactor for extracellular superoxide dismutase (SOD3), linking GHK-Cu to the antioxidant arm of tissue regeneration.
Research Applications
- Matrix remodeling and extracellular matrix research
- Collagen and decorin synthesis studies
- Hair follicle biology and dermal papilla activation
- Photoaging and UV-damage recovery investigations
- Anti-inflammatory and antioxidant pathway research
- Bone density, osteoblast differentiation, and dental repair models
Product Specifications
- Quantity: 50mg per vial
- Purity: ≥98% (HPLC verified)
- Molecular Formula: C₁₄H₂₄CuN₆O₄
- Molecular Weight: 402.93 g/mol
- Form: Lyophilized powder
- Storage: Refrigerate after reconstitution
- Testing: Third-party lab tested, COA available on request
For research purposes only. Not for human or veterinary use.
