AHK-Cu (RAW) 1g

AHK-Cu (RAW) 1g — Alanyl-L-Histidyl-L-Lysine Copper-Binding Tripeptide AHK-Cu in its raw lyophilized form is the unloaded tripeptide Ala-His-Lys, supplied for bulk research applications where the user controls copper-loading stoichiometry at reconstitution. AHK is a structural analog of GHK with the N-terminal glycine substituted by alanine, which alters the copper-binding pocket geometry and produces a distinct profile in hair-follicle and skin-research models. Mechanism of Action AHK forms a coordination complex with divalent copper analogous to GHK-Cu but with subtly different binding kinetics and tissue distribution. Preclinical research has characterized AHK-Cu's particular affinity for hair-follicle dermal-papilla cells, where it has been investigated for its action on vascular endothelial growth factor (VEGF) signaling and follicular angiogenesis. Comparative studies against GHK-Cu and biotinyl-GHK frequently use AHK-Cu as a reference peptide for studies isolating copper-coordination effects from sequence-specific receptor binding. Research Applications Hair-follicle dermal-papilla research VEGF signaling and angiogenesis studies Copper-binding peptide comparative pharmacology Topical cosmetic peptide formulation research Tissue-remodeling enzyme expression investigations Product Specifications Quantity: 1g (1000mg) per vial, RAW (no copper-loading) Purity: ≥99% (HPLC verified) Molecular Formula: C₁₅H₂₆N₆O₄ (base peptide, pre-Cu) Molecular Weight: 354.41 g/mol (base peptide) Sequence: Ala-His-Lys Form: Lyophilized powder, raw tripeptide Storage: Refrigerate after reconstitution Testing: Third-party lab tested, COA available on request For research purposes only. Not for human or veterinary use.