Description
Product details
Selank: Tuftsin-Derived Heptapeptide Research Peptide
Selank is a synthetic heptapeptide derived from the immunomodulator tuftsin, originally developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Its Pro-Gly-Pro C-terminus extends in-vivo half-life and enables stable intranasal bioavailability in preclinical models, which has made it a workhorse of cognitive and stress-response peptide research for more than two decades.
Mechanism of Action
Preclinical studies show Selank modulates expression of brain-derived neurotrophic factor (BDNF), influences monoamine neurotransmitter tone (serotonin, dopamine, norepinephrine), and produces measurable shifts in hippocampal gene expression related to neuroplasticity. Unlike benzodiazepines, Selank does not directly bind GABA-A receptors; it modulates GABAergic activity indirectly through enkephalin and monoaminergic pathways, which is the dominant hypothesis for its non-sedating stress-response profile in animal models.
Research Applications
- Anxiety-related behavior in rodent models
- Cognitive performance and attention investigations
- BDNF expression and neuroplasticity studies
- Stress-axis modulation research
- Enkephalin and monoamine system interaction studies
Product Specifications
- Quantity: 10mg per vial
- Purity: ≥99% (HPLC verified)
- Molecular Formula: C₃₃H₅₇N₁₁O₉
- Molecular Weight: 751.88 g/mol
- Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Form: Lyophilized powder
- Storage: Refrigerate after reconstitution
- Actual Tested Value: 10.4 mg
For research purposes only. Not for human or veterinary use.
